Assistant Professor / Attending Physician
Sarah is a physician-scientist whose long-term goal is to understand the role of T cell dysfunction in chronic allergic and inflammatory disease, including asthma and obesity, as well as rare, monogenic primary immunodeficiency. To this end, she uses complementary approaches in humans and mice, leveraging detailed immunophenotyping and metabolic characterization of immune dysfunction in patients to identify mechanistic hypotheses to test in mouse models and human cells in vitro.
Eric Abrams
Clinical Research Assistant II
Eric focuses on patient recruitment, sample collection, and IRB management. He works on multiple projects within the lab that aim to understand healthy immune system development, immunometabolic dysregulation, and the impact of obesity on immune function. He has multiple years of experience in clinical research and patient care with a background in biology. Outside of the lab, Eric enjoys going on hikes, taking ski trips, and reading.
Megan Dalalo
Undergraduate Researcher
Megan is an undergraduate student on the pre-med track studying Biomedical Science in the School of Engineering at UPenn. She aims to explore the field of immunology and more specifically, immune cell dysregulation.
Montana Knight
Bioinformatics Scientist
Montana is a member of the Department of Biomedical Health Informatics at CHOP. She works with a variety of large biological datasets in the lab. Her expertise lies in multi-omic data processing, with a current focus on bulk and single cell RNA sequencing data analysis. When she isn’t on her computer, you can find her walking her dog or losing a game of Quizzo at a local restaurant.
Andrea Mauracher
Postdoctoral Fellow
Andrea conducted her M.D. Ph.D. at the University Children’s Hospital of Zurich, Switzerland, where she focused on diagnosing and studying various Inborn Errors of Immunity. She has joined the lab to conduct her postdoctoral research on the effects dysregulated STAT signalling has on CD8 T cell function.
Senior Research Associate, Lab Manager
Samir has 15 years of chemistry and biochemistry experience with a focus on translational research and lab management.
Jose Campos
Graduate Student (IGG Ph.D. Program)
Jose is an Immunology Ph.D. candidate with a background in tumor immunology, adoptive cellular therapies, and T cell signaling. For his thesis studies, Jose focuses on defining mechanisms of CD8+ T cell dysregulation in STAT3 GOF syndrome, a rare and complex genetic disorder. Outside of lab you can find Jose on his bike riding centuries, at trivia, or finding new restaurants to eat at.
Ceire Hay
Graduate Student (IGG Ph.D. program)
Ceire is a Ph.D. student with three years of experience using mouse model systems to investigate T cell trafficking mechanisms in the context of cancer and immunotherapy. As a rotation student she focuses on understanding the role of T cell dysfunction in asthma and obesity.
Brad Lindell, M.D.
Assistant Professor / Attending Physician
Brad is a pediatric intensivist whose goal is to understand the role of immune function in pediatric critical illness. His research focuses on leveraging high-dimensional analysis of clinical data and deep immunophenotyping to identify biologically distinct cohorts of children with sepsis and multiple organ dysfunction syndrome.
Saptarshi Roy
Research Associate
Saptarshi did his Ph.D. at CSIR-Indian Institute of Chemical Biology; India, and his research aimed to understand the immunological aspects of host parasite interaction. Then, he did his postdoctoral research at the University of Pennsylvania with a focus on deciphering the role of mast cells in allergy and asthma. Saptarshi joined the lab as Research Associate to investigate the role of endogenous retroelements in mediating T cell exhaustion in obese asthma in mice. He is also working on understanding how obesity impacts vaccine efficacy. Outside of research, his major interest is in sports.
Maryia Svirydava
IGG, M.D. Ph.D. Student
Mary is an M.D. Ph.D. student in Immunology. Her main interest is in T cell dysfunction in inborn errors of immunity. In her free time, Mary paints, eats pastry, and reads a lot of fantasy.
Former Lab Members
Rotation Students
Isabel Breuer – CAMB Ph.D. Student
Mark Dittmar – CAMB MVP Ph.D. Student
Diego Espinoza – IGG, M.D. Ph.D. Student
Xingyuan Fang – Biology Ph.D. Student
Alana McSween – IGG Ph.D. Student
Molly Nelson – IGG Ph.D. Student
Research Staff
Peyton Conrey – Technician
Chao Di – Bioinformatics Scientist
Elena Gonzalez – Clinical Research Coordinator I
Pooja Gunnala – Clinical Research Coordinator
Cristina Jasen – Clinical Research Assistant
Post-Doctoral Trainees
Sajad Ahmad Bhat – Postdoctoral Fellow
Amandeep Sandhu – Clinical Fellow
Student Researchers
Alexander Howe – Undergraduate Researcher
Arjun Kumar – High School Researcher